Original Antigenic Sin — The Hidden Danger of COVID Shots

Original Antigenic Sin — The Hidden Danger of COVID Shots by Dr. Joseph Mercola for Dr Mercola’s Censored Library – SubStack

Due to a process known as ‘immune imprinting,’ which handcuffs your immune system, we could well be facing the ‘dark winter’ President Biden warned would befall us.

STORY AT-A-GLANCE

  • Scientists warn repeated COVID boosters may result in lowered immunity through a process known as “original antigenic sin” or “immune imprinting”
  • Original antigenic sin describes how your first exposure to a virus shapes the outcome of subsequent exposures to antigenically related strains. The end result is that you become increasingly prone to symptomatic infections
  • Data from the U.S. Centers for Disease Control and Prevention confirm that people who got two or three COVID jabs are MORE likely to get ill with COVID six to eight months after the last dose than had they gotten none
  • Health authorities are potentially worsening matters further by pushing people to simultaneously get the updated bivalent COVID booster and a quadrivalent flu vaccine this fall
  • The COVID jab and the flu vaccine are the No. 1 and No. 2 most dangerous injections respectively, based on adverse event reports and payouts from the U.S. Vaccine Injury Compensation Program. Both are also capable of shedding, and both can make you more prone to infection as their protection wears off

COVID-19 has been going on for nearly three years, and with a whole new set of untested COVID boosters being rolled out, some scientists are taking a step back, cautioning that there still are unanswered questions about how the shots work.

They say more research needs to be done on what is known as “original antigenic sin,” aka “immune imprinting,” which refers to how your immune system responds to repeated introductions of the COVID variants.


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Understanding Original Antigenic Sin

The following description of original antigenic sin was published in a January 2019 Journal of Immunology paper titled “Original Antigenic Sin: How First Exposure Shapes Lifelong Anti–Influenza Virus Immune Responses”:1

“The term ‘original antigenic sin’ (OAS) was first used in the 1960s to describe how one’s first exposure to influenza virus shapes the outcome of subsequent exposures to antigenically related strains. In the decades that have passed, OAS-like responses have been shown to play an integral role in both protection from and susceptibility to infections.

OAS may also have an important deterministic role in the differential efficacy of influenza vaccine responses observed for various age cohorts across seasons …

OAS describes the phenomenon whereby the development of immunity against pathogens/Ags is shaped by the first exposure to a related pathogen/Ag … subsequent infections with similar influenza virus strains preferentially boost the Ab response against the original strain …

The critical role of primary exposure in shaping the composition of the Ab repertoire was not only observed in humans after influenza virus infections; this phenomenon was also observed in animal models and in the context of other infectious agents.

For example, additional serum absorption experiments in ferrets infected in succession with three different influenza virus strains demonstrated that nearly all of the host Abs after the infection series were reactive against the first strain, only a fraction of serum Abs could be absorbed by the secondary virus, and fewer yet by the tertiary virus.”

Simplified Example

Here’s a layman’s summary to illustrate this phenomenon as simply as possible, within the context of COVID:

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