Melanin: The Holy Grail Of Radioprotective Food Compounds By Sayer Ji for Green Med Info
Could the melanin found in our bodies and in foods like mushrooms help to mitigate the increasingly dire quantities of radiation we are exposed to daily?
Over the course of the past decade, one of the most interesting concepts I have run into while scouring the biomedical literature is the possibility that melanin’s biological role in the human body may extend far beyond simply protecting us against UV radiation. In fact, one recent and highly controversial paperproposes that melanin is responsible for generating the majority of the body’s energy, effectively challenging the ATP-focused and glucose-centric view of cellular bioenergetics that has dominated biology for the past half century.
Research is now emerging indicating that melanin may function in a manner analogous to energy harvesting pigments such as chlorophyll, and may have even have driven our evolution into the uniquely hairless, brain-dominant hominins we are today. While melanin’s proposed ability to convert sunlight into metabolic energy has amazing implications (one of which is the taxonomical reclassification of our species from heterotrophic to photoheterotrophic), what may have even more spectacular implications is the prospect that melanin may actually both protect us against ionizing radiation and transform some of it into metabolically useful energy.
In a day and age where radioisotopes from nuclear weapons testing, routine releases from the nuclear, fracking, and coal-fired power industries, and more recently, global fallout from the Chernobyl and Fukushima meltdowns, are increasingly accumulating in the environment, food chain, and our bodies, reducing radiotoxicity and/or enhancing detoxification mechanisms should be a universal concern. Add in the unavoidable onslaught of medical, cell phone communications and WiFi technology, and air travel associated radiation exposures, and you can virtually guarantee your body burden of radiation exposure is significant and represents a serious health risk.
While GreenMedInfo.com now contains an extensive database of radiation toxicity mitigating substances which can be viewed both on the Radiation Disaster Toxicitypage, and the radioprotective actions page, we have not until now reported specifically on melanin’s potential to offset radiation exposure.
Melanin’s Mysterious Properties
Melanin is, indeed, one of the most interesting biomolecules yet identified. The first known organic semiconductor, it is capable of absorbing a wide range of the electromagnetic spectrum (which is why it appears black), most notably, converting and dissipating potentially harmful ultraviolet radiation into heat. It serves a wide range of physiological roles, including free radical scavenging, toxicant chelation, DNA protection, to name but a few. It is also believed to have been one of the original ingredients essential for life on this planet. I’ve reported previously on its potential in converting sunlight into metabolic energy, but converting ionizing gamma radiation into useful energy? Beyond the realm of comic book heroes, who would have ever thought such a thing possible?
The first time (I am aware of) that this possibility surfaced in the literature was a 2001 Russian report on the discovery of a melanin-rich species of fungi colonizing and apparently thriving within the walls of the still hot Chernobyl meltdown reactor site.1 In 2004, the same observation was made for the surrounding soils of the Chernobyl site.2 We also know that, based on a 2008 report, pyomelanin-producing bacteria have been found in thriving colonies within uranium-contaminated soils.3There is also a 1961 study that found, amazingly, melanin-rich fungi from soils of a Nevada nuclear test site survived radiation exposure doses of up to 6400 Grays (about 2,000 times a human lethal dose!).4 Clearly, something about melanin in these species not only enables them to survive radiation exposures that are normally lethal to most forms of life, but actually attracts them to it. Could the fungi actually be using melanin to ‘feast’ on the free lunch of anthropogenic radioactivity?
This article is copyrighted by GreenMedInfo LLC, 2022
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