Bill Gates and Intellectual Ventures Funds Microchip Implant Vaccine Technology By: Celeste McGovern for Green Med Info
The Bill and Melinda Gates Foundation has donated more than $21 million towards developing a vaccine technology that uses a tattoo-like mechanism which injects invisible nanoparticles under the skin that is now being tested in a vaccine against the virus that causes COVID-19
The microneedle technology is also being wed to injectable technology, funded by the Bill and Melinda Gates Foundation, which embeds under the skin a vaccination record visible by near infrared light that can be read by smartphone technology.
The Bill and Melinda Gates Foundation is funding the technologies with aims to enable them in “house-to-house” vaccine campaigns undertaken by people with “minimal training.”
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Researchers from the University of Pittsburgh reported in their studypublished April 1 in EBiomedicine, a Lancet Journal, that their microneedle patch vaccine against the SARS CoV-2 virus that causes COVID-19 “prompted robust antibody production in the mice within two weeks.”
The patches resemble a spiky piece of Velcro, with hundreds of tiny microneedles made of sugar. The needles prick just into the skin and quickly dissolve, releasing the vaccine into the tiny abrasions and inducing a potent immune cell response despite the minute amount of the vaccine material – far more potent than an intramuscular injection.
The researchers had been testing vaccine using the microneedle patch for other coronaviruses, including the one that causes Middle East Respiratory System (MERS) and reported that three different experimental MERS vaccines induced the production of antibodies against the virus. These responses were stronger than the responses generated by regular injection of one of the vaccines along with a powerful immune stimulant (an adjuvant). Antibody levels continued to increase over time in mice vaccinated by microneedle patch-up to 55 weeks, when the experiments ended. The researchers have now turned their technology to the COVID-19 virus, SARS CoV-2.
“Testing in patients would typically require at least a year and probably longer,” senior co-author of the study, dermatology professor Louis Falo said.“This particular situation is different from anything we’ve ever seen, so we don’t know how long the clinical development process will take. Recently announced revisions to the normal processes suggest we may be able to advance this faster.”
Another studyfunded by the Bill and Melinda Gates Foundation and published in December, 2019 by researchers from the Massachusetts Institute of Technology, the Institute of Chemistry of the Chinese Academy of Sciences in Beijing and the Global Good, Intellectual Ventures Laboratory in Bellevue, WA, describes how “near-infrared quantum dots” can be implanted under the skin along with a vaccine to encode information for “decentralized data storage and bio-sensing.”
“To maximize the utility of this technology for vaccination campaigns, we aimed to create a platform compatible with microneedle-delivered vaccines that could reliably encode data on an individual for at least five years after administration,” said the MIT paper, titled Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination. “In addition, this system also needed to be highly biocompatible, deliver a sufficient amount of dye after an application time of 2Â min or less, and be detectable using a minimally adapted smartphone.”
